THE IMPORTANCE OF A GOOD NIGHTS SLEEP
Everybody knows that great feeling after getting a good night’s sleep. You wake in the morning feeling refreshed, physically and mentally ready to face the day. Conversely, we all know the feeling of fatigue after a poor night’s sleep and the struggle it can be to perform even the most basic of tasks throughout the day. Even though we know how good sleep is for us, in our increasingly busy society, many of us are not getting the quality sleep needed to truly receive the health benefits of sleep.
Adequate sleep is a key part of a healthy lifestyle, and can benefit your heart, weight, mind, and more. The importance of sound sleep cannot be underestimated when considering one’s health and wellbeing. Along with nutritious food, exercise and social interaction, effective sleep is one of the non-negotiable cornerstones of a healthy life. Insufficient sleep greatly reduces quality of life and increases the risk of physical and mental health problems1, and yet, approximately 1/3 of adults experience occasional insomnia, and 6-10% of us suffer severely.2,3
WHAT CAUSES SLEEPLESSNESS?
There are numerous things that can contribute to sleeplessness, including your sleeping habits, lifestyle choices, and medical conditions. Some causes are minor and temporary while others are serious enough to affect our normal physical, mental, social and emotional wellbeing.
Minor and temporary causes of sleeplessness can include consuming too much caffeine, use of blue light devices (smart phones/tablets) before bedtime, and excessive or unpleasant noise disturbances. Other things that can disrupt our sleep can be frequent urination, jet lag, physical pain, the use of certain medications, and aging.
Stress, worry, anxiety and depression are some of the most common causes of sleeplessness in some people. Sleeping problems may also be related to having an actual sleeping disorder such as insomnia, sleep apnea, sleep walking, night terrors and restless legs syndrome.
WHAT IS PURAZ SLEEP MANAGER?
Sleep from within. Scientifically formulated, Puraz Sleep Manager supports your body's own natural ability to sleep soundly and deeply. This cutting-edge formula is at the very forefront in sleep support, developed specifically for those people who are having difficulty in getting to sleep, staying asleep, or both.
Sleep Manager is a high-end sleep support supplement designed to give noticeable results. Methodically formulated, it uses only clinically researched ingredients at optimal doses. The all natural, safe formula works to support biochemical ‘relaxation and sleep’ pathways, without the side-effects or risk of dependency so you can wake feeling fresh and energised each and every day. The refreshing natural lemon flavour makes it easy and convenient to take.
Every active ingredient in Sleep Manager has been scientifically researched and shown to support a healthy, quality sleep. The key active ingredients their role in sleep support are:
Glycine is an amino acid and neurotransmitter. Supplementation with glycine has been shown in research to support sleep quality. A 2007 placebo-controlled trial involving ingestion of 3g of glycine at bedtime suggests that this dose both promotes and stabilises sleep and leads to subjective feelings of having slept well. Participants also felt more awake the next day and performed better on memory recognition tasks than placebo.4 In another study, people that had restricted sleep time reported feeling mentally sharper and less fatigued after pre-sleep glycine ingestion.5 A key feature of natural sleep initiation is a lowering of core body temperature. Human and animal trials show that glycine lowers core body temperature in a similar way to some pharmaceuticals such as benzodiazepines.
Research shows elevated levels of the stress hormone cortisol are linked with insomnia and restless sleep. Taurine is an amino acid that supports the reduction of cortisol levels and the production of GABA, which is a major inhibitory neurotransmitter—our bodies’ own natural “off” switch. Taurine is well known for its anti-anxiety effect, providing support for a calm nervous system and promoting feelings of relaxation and tranquillity to lower stress and the running thoughts that can hinder a restful sleep.6
Uridine is a cutting-edge nucleotide sleep-support substance. Uridine is found throughout the body and brain, has a relaxing effect on the central nervous system, and is naturally at its highest level during the period of least movement during sleep. It is thought to be partly responsible for the hypnotic effect that human breastmilk has on babies. Studies have shown that nightly intake of low-dose uridine increases the number of both REM and non-REM sleep episodes.7
Tryptophan is a nutritional sleep aid of which consumption at night has been shown to support serotonin and melatonin production. A decades-long body of research suggests that tryptophan supplementation reduces sleep latency (time taken to fall asleep), increases night-time sleepiness and improves morning wakefulness in insomniacs and healthy people that have an abnormally long sleep latency.8
Magnesium is well known to promote a deep and relaxed sleep through supporting a calm mind, easing worry, muscle tension and stress. Research shows that magnesium improves both subjective (ISI score, sleep efficiency, sleep time and sleep onset latency, early morning awakening) and objective (concentration of serum renin, melatonin, and serum cortisol) measures of sleep quality and duration in elderly insomniacs.9
Other Supporting Ingredients
Phosphatidylserine - stress and anxiety support.
Vitamin B6 - supports sleep quality, vivid dreaming and dream recall.
Vitamin B1 and B3 - both play a variety of supporting roles in the sleep process.
Zinc - natural mineral that supports the body’s need for repairing tissue during deep sleep. It relaxes muscles for a restful, rejuvenating sleep.
1. Kennaway, D.J., Programming of the fetal suprachiasmatic nucleus and subsequent adult rhythmicity. Trends in Endocrinology and Metabolism: TEM, 2002. 13(9): p. 398-402.
2. Ohayon M. Epidemiology of insomnia: what we know and what we still need to learn. Sleep Med Rev 2002;6:97-111.
3. Morin CM, LeBlanc M, Daley M, Grégoire JP, Mérette C. Epidemiology of insomnia: Prevalence, self-help treatments, consultations, and determinants of help-seeking behaviors. Sleep Medicine, in press
4. Yamadera, W., et al., Glycine ingestion improves subjective sleep quality in human volunteers, correlating with polysomnographic changes. Sleep and Biological Rhythms, 2007. 5(2): p. 126-131.
5. Bannai, M., et al., The effects of glycine on subjective daytime performance in partially sleep-restricted healthy volunteers. Frontiers in Neurology, 2012. 3: p. 61.
6. Jia, F., et al., Taurine is a potent activator of extrasynaptic GABA(A) receptors in the thalamus. The Journal of Neuroscience: the official journal of the Society for Neuroscience, 2008. 28(1): p. 106-15.
7. Sanchez, C.L., et al., The possible role of human milk nucleotides as sleep inducers. Nutritional Neuroscience, 2009. 12(1): p. 2-8.
8. Silber, B. Y., & Schmitt, J. a J. (2010). Effects of tryptophan loading on human cognition, mood, and sleep. Neuroscience and Biobehavioural Reviews, 34(3), 387–407. doi:10.1016/j.neubiorev.2009.08.005
9. Abbasi, B., Kimiagar, M., Sadeghniiat, K., Shirazi, M. M., Hedayati, M., & Rashidkhani, B. (2012). The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. Journal of Research in Medical Sciences: The Official Journal of Isfahan University of Medical Sciences, 17(12), 1161–9.
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|INGREDIENTS (Serving Size: 5.5g)
||(MG PER SERVE)
|Magnesium (from Citrate)
|Vitamin C (Ascorbic acid)
|Vitamin B1 (Thiamine HCL)
|Vitamin B3 (Niacinamide)
|Vitamin B6 (Pyridoxal-5-Phosphate)
|Inactive ingredients: Natural lemon flavour, Organic stevia extract
*Derived from Soy (non-GMO)
Contents: 166g powder.
Directions: Take one level scoop dissolved in water 30-90 minutes before bedtime.
Cautions: This product should not be taken during pregnancy or lactation. Always read the label and use only as directed. Should not be taken with anti-depressants, sleeping medication or other prescription medications without medical advice. Store below 25°C in a dry place. Keep out of reach of children. Do not exceed recommended intake.